Hierarchical Custom Settings can be used to bypass all triggers, validation rules, process builders and workflow rules.

Custom Settings to Bypass:

Bypass in Validation Rules:

Bypass in Workflow Rules:

Bypass in Trigger:

Bypass in Process Builder:

Custom Settings record to Bypass:

After setting the data in custom settings for user Test as above, it will bypass Validation Rules, Workflow Rules, Triggers, and Process Builders.